Fitness Improvement in Obese, Pregnant Women: an Intervention Trial (InterGOFIT)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Weekly time spent at physical activity of moderate intensity and above
研究概览
简要总结
In pregnancy, the adoption or pursuit of a sedentary lifestyle contributes to the development of co-morbid conditions such as hypertension, maternal and childhood obesity, gestational diabetes, pre-eclampsia, cesarean section and delivery of large-for-gestational-age infants (LGA).
The aim of this study is to test the hypothesis that obese, pregnant women following a supervised moderate intensity physical conditioning program during the 2nd trimester of pregnancy will maintain a higher level of physical activity up to the end of pregnancy, as compared to women in the control group. We will also conduct a pilot study on the feasibility to examine the effects of the intervention on maternal fitness and neonatal anthropometry.
详细描述
Looking at the multiple needs of pregnant women with obesity, physical conditioning may offer a great opportunity to improve fitness and to decrease cardio-metabolic disturbances, to prevent excessive weight gain, to improve general health status, and to reduce health care utilization. Furthermore, beneficial effects of fitness on adverse maternal health outcomes related to obesity might decrease the development of long-term obesity and metabolic repercussions in the offspring.
The Society of Obstetricians and Gynaecologists of Canada (SOGC) recommends that all women without contraindication be encouraged to participate in aerobic and strength-conditioning exercises as part of a healthy lifestyle during pregnancy. Despite these recommendations, obese women are inactive during pregnancy and are currently still at high risk of poor physical fitness.
Thus, although exercise clearly improves maternal health status and thus potentially prevents adverse perinatal outcomes, obese pregnant women poorly adhere to experts' recommendations about the need for exercise during pregnancy. Therefore, this situation justifies the need to develop adapted strategies aimed at increasing the implementation of guideline recommendations in this population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •pregnant women 18 years or older
- •single pregnancy
- •delivery at Centre Hospitalier Universitaire de Québec
- •pre-pregnancy BMI ≥30 kg/m2
排除标准
- •multiple pregnancy
- •diabetes or chronic hypertension prior to pregnancy
- •uncontrolled thyroid problems
- •exercise contraindications
结局指标
主要结局
Weekly time spent at physical activity of moderate intensity and above
时间窗: At 36 weeks of gestation
Accelerometry data (minutes per week spent over selected cutpoints)
次要结局
- Gestational weight gain(At 36 weeks of gestation)
- Muscular fitness(At 28 wks of gestation)
- Cardiorespiratory fitness(At 28 weeks of gestation)
- Energy Expenditure(At 36 weeks of gestation)
- Neonatal anthropometry(At delivery)
- Fetal growth(At 28 weeks of gestation)