Mechanism-based modular psychotherapy for adolescents and young adults with trauma: a feasibility study

Phase 2

Recruiting

• Conditions: Mental health disorders according to DSM-5, as measured by the Short Interview for Mental Disorders (Mini-DIPS; Margraf & Cwik, 2017) as well as subparts of the Structured Clinical Interview for DSM-5 disorders and the Structured Clinical Interview for Personality Disorders (SCID-5-CV and SCID-5-PD, Beesdo-Baum, K., Zaudig, M., & Wittchen, 2019).

• Registration Number: DRKS00034058
• Lead Sponsor: DZPG (Deutsches Zentrum für Psychische Gesundheit)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-04-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

•At least one diagnosis of a mental health disorder according to the DSM-5, as assessed by means of Mini-DIPS (Magraf & Cwik, 2017; for exceptions see exclusion criteria), the Structured Clinical Interview (SCID-5-CV, only the subset of questions dealing with ADHS, Beesdo-Baum, K., Zaudig, M., & Wittchen, 2019), and the Structured Clinical Interview for Personality Disorders (SCID-5-PD, Beesdo-Baum, K., Zaudig, M., & Wittchen)
•At least 1 cut-off of the following measures is exceeded: 1) Rejection Sensitivity Questionnaire (RSQ = 9.88), 2) Brief Version of the Difficulties in Emotion Regulation Scale (DERS-16 = 55.73), or 3) Interpersonal Relationships” subscale of the Outcome Questionnaire-45 (EB-45 = 13)
•Traumatic experiences in childhood and/or adolescence: moderate to severe scores on one of the subscales of the Childhood Trauma Questionnaire (CTQ; Klinitzke et al., 2012) according to Häuser and colleagues (2011)
•Fluent in German
•Health insurance

Exclusion Criteria

-Posttraumatic stress disorder, as assessed with Mini-DIPS (Margraf & Cwik, 2017)
-moderate or severe substance abuse disorder (exception: cannabis), as assessed with Mini-DIPS (Margraf & Cwik, 2017)
-currently suffering from acute psychotic symptoms, as assessed with Mini-DIPS (Margraf & Cwik, 2017)
-currently suffering from acute manic symptoms, as assessed with Mini-DIPS (Margraf & Cwik, 2017)
-Autism spectrum disorder, as assessed with the short version of the Autism spectrum quotient questionnaire (AQ-10; Allison et al., 2012)
-currently participating in another psychotherapy
-severe cognitive impairment (IQ < 70), as assessed with mini-q (Baudson & Preckel, 2015)
-not being able or willing to not use substances in therapy sessions, as clinically assessed on an individual basis
-imminent risk of suicide, as clinically assessed on an individual basis
-Severe illness which prevents study patients from regularly participating in therapy sessions, as clinically assessed on an individual basis
-Change in or start of psychotropic medication less than two weeks before study begin (for fluoxetine less than three weeks).

Exclusion criteria for MRT:
-Potential pregnancy or confirmed pregnancy
-Claustrophobia
-Metal pieces inside the body or on the body, including tattoos, permanent make-up and micro-blading
-Difficulty with vision > 6 dioptres and no contact lenses

Study & Design

• Study Type: interventional
• Study Design: Not specified