Active Versus Non Active Drainage for the Treatment of Infected Intra-abdominal Collection: a Randomized Prospective Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- time of drainage
研究概览
简要总结
The Percutaneous drainage of symptomatic intra-abdominal collection (primary or secondary to surgery)is the treatment of choice in the absence of peritonitis signs. In critically ill patients, this procedure allows to avoid or postpone surgery. In these settings, the percutaneous drain can be either in Active Vacuum Pressure or in Free drainage. However, no prospective trials has assessed the efficiency of these two modalities of drainage in cases of infected intra-abdominal collections. The investigators aimed then to prospectively analyzed the efficiency (in term of infectious control) of drainage under active vacuum pressure vs. free drainage for the treatment of infected intra-abdominal collections.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Infected intra-abdominal collection requiring a percutaneous drainage after surgery or due to a primary intra-abdominal infectious disease (e.g. diverticulitis, appendicitis)
- •age over 18 years old
- •intra-abdominal collections >5 cm in diameter with signs of infections on imaging
排除标准
- •pregnancy
- •age< 18 years
- •signs of peritonitis
- •Intensive care unit patients
结局指标
主要结局
time of drainage
时间窗: 90 days after drianage
次要结局
- Control of infection(up to 7 days after drainage)
- Timing of antibiotherapy(up to 15 days after drainage)
- Hospital stay(up to 90 days after drainage)
- Morbidity related to the procedure(up to 90 days after drainage)
- in-hospital mortality(up to 90 days after the drainage)
研究者
Dr. Emmanuel Melloul
Surgeon, M.D.
Centre Hospitalier Universitaire Vaudois