JPRN-jRCT2031200442进行中（未招募）2 期
A Phase 2, Randomized, Open-label Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Hepatocellular Carcinoma Who Are Naive to IO Therapy But Progressed on Tyrosine Kinase Inhibitors
David Perez Callejo0 个研究点目标入组 24 人开始时间: 2021年3月25日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 24
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 18age old 至 ot applicable（—）
- 性别
- All
入选标准
- •Must have a diagnosis of hepatocellular carcinoma(HCC)based on histological confirmation
- •- Must have advanced/metastatic HCC
- •- Have to be immunotherapy treatment-naive; no prior immunotherapies are permitted
- •- Must have at least one Response Evaluation Criteria in Solid Tumors(RECIST)v1.1 measurable untreated lesion
- •- Child-Pugh score of 5 or 6
- •- Eastern Cooperative Oncology Group(ECOG)performance status 0 or 1 for ECOG performance status scale
排除标准
- •- Known fibrolamellar HCC, sarcomatoid HCC, combined hepatocellular cholangiocarcinoma
- •- Prior organ allograft or allogeneic bone marrow transplantation
- •- No uncontrolled or significant cardiovascular disease
- •- No active known autoimmune disease
研究者
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