The Microcirculation in Acute Myocardial Infarction (Micro-AMI)

University of Bristol1 site in 1 country50 target enrollmentMarch 2012

ConditionsSTEMI

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: STEMI
Sponsor: University of Bristol
Enrollment: 50
Locations: 1
Primary Endpoint: Microvascular obstruction
Status: Completed
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study investigates the association between the microvascular resistance at the time of primary percutaneous intervention, with microvascular obstruction on CMR and blood markers of myocardial damage.

Registry

clinicaltrials.gov

Start Date

March 2012

End Date

January 2014

Last Updated

11 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Bristol

Responsible Party

Principal Investigator

Elisa McAlindon

Clinical Research Fellow

University of Bristol

Eligibility Criteria

Inclusion Criteria

•\>18 years old
•Cardiac symptoms of \> 20 mins chest pain or equivalent.
•ECG criteria consistent with STEMI (STEMI)
•Proceeding with percutaneous angioplasty
•Assent/ consent to the study

Exclusion Criteria

•Known allergy to adenosine or gadolinium
•Chronic atrial fibrillation
•Renal impairment with eGFR \<30
•Contraindication to angiography
•Contraindication to CMR (implanted pacemaker/ defibrillator, ferromagnetic metal implant/ injury, claustrophobia, obesity/ too large for CMR scanner)
•Cardiogenic shock
•Patients with special communication needs or altered consciousness.
•Patients who do not give assent/consent to the study