Comparison of Postoperative Pain After Application of Aloe Vera Gel Dressings With Conventional Paraffin-Based Tulle Dressings at Split-Thickness Skin Graft Donor Site
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- Pain Score at Donor Site on Postoperative Day 7
研究概览
简要总结
The goal of this clinical trial is to learn if Aloe Vera gel dressing helps reduce pain better than traditional paraffin-based tulle dressing at the donor site of split-thickness skin grafts in adult patients aged 18 to 60. The main questions it aims to answer are:
Does Aloe Vera gel dressing reduce postoperative pain more effectively than paraffin-based tulle dressing on the 7th day after surgery?
Is there a difference in the need for additional pain medication between the two groups?
Researchers will compare Aloe Vera gel dressing to paraffin-based tulle dressing to see if Aloe Vera leads to better pain control.
Participants will:
Undergo split-thickness skin graft surgery
Receive either Aloe Vera gel dressing or paraffin-based tulle dressing at the donor site
Have pain measured using a visual analogue scale (VAS) on the 7th day after surgery
Be given pain medication if their pain score is 4 or higher, and the amount used will be recorded
详细描述
This randomized controlled trial aims to evaluate the effectiveness of Aloe Vera gel dressings compared to conventional paraffin-based tulle dressings in reducing postoperative pain at the donor site of split-thickness skin grafts (STSG). The study will be conducted in the Department of Plastic Surgery, Mayo Hospital, Lahore, over a period of six months.
Split-thickness skin grafting is a common reconstructive surgical procedure. Although effective, it creates a donor site wound that often causes significant postoperative pain, potentially affecting patient recovery and satisfaction. While paraffin-based tulle dressings are widely used, they may not offer optimal pain relief. Aloe Vera gel, due to its anti-inflammatory, analgesic, and wound-healing properties, is a promising alternative that has shown benefit in burn wounds and other superficial skin injuries.
A total of 72 patients (aged 18-60 years, of either gender) requiring STSG will be enrolled and randomized into two equal groups:
Group A will receive Aloe Vera gel dressings applied directly to the donor site.
Group B will receive conventional paraffin-based tulle dressings.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Patients aged 18-60 years of age of either gender needing Split thickness skin graft
排除标准
- •• Patients known to have exaggerated/diminished pain response due to certain medical conditions (e.g. diabetes, neuropathy, chemotherapy, opioids etc.)
- •Patients allergic to either dressings
研究组 & 干预措施
Aloe Vera Gel Dressing
Participants in this group will receive Aloe Vera gel applied directly to the split-thickness skin graft donor site
干预措施: Aloe Vera Gel Dressing (Other)
Paraffin-Based Tulle Dressing (Conventional Dressing)
Participants in this group will receive standard paraffin-based tulle dressing with chlorhexidine on the donor site.
干预措施: Paraffin-Based Tulle Dressing (Other)
结局指标
主要结局
Pain Score at Donor Site on Postoperative Day 7
时间窗: 7 days after surgery
Postoperative pain will be measured using the Visual Analogue Scale (VAS), which ranges from 0 (no pain) to 10 (worst possible pain).
次要结局
未报告次要终点