Epidemiological Profile and Therapeutic Management of Patients Diagnosed With Cutaneous T-cell Lymphoma Evaluated in the Dermatology Department of Hospital México During the Period From 2019 to 2025.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 350
- 试验地点
- 1
- 主要终点
- Characterize the epidemiology
研究概览
简要总结
Adult patients (≥18 years) with confirmed cutaneous T-cell lymphoma evaluated at Hospital México between 2019 and 2025 will be retrospectively analyzed using EDUS records to describe their epidemiological profile, clinical characteristics, treatments, and outcomes.
详细描述
This retrospective observational study will analyze adult patients (≥18 years) with a confirmed diagnosis of cutaneous T-cell lymphoma evaluated in the Dermatology Service of Hospital México between January 2019 and December 2025. Data will be obtained from electronic medical records (EDUS), including sociodemographic characteristics, clinical presentation, histopathological and immunohistochemical findings, disease staging, treatment modalities, and clinical outcomes.
Patients must have at least one documented dermatological evaluation and have received treatment, including skin-directed therapies and/or systemic therapies. Records that are incomplete, inconsistent, or lack histopathological confirmation will be excluded.
The study aims to characterize local epidemiological and therapeutic patterns and describe clinical outcomes using descriptive statistical analysis, providing updated real-world evidence to support clinical decision-making and optimize management strategies for cutaneous T-cell lymphoma in a national referral center.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with a confirmed diagnosis of cutaneous T-cell lymphoma, established through clinical, histopathological, and immunohistochemical criteria, documented in EDUS of Hospital México in the Dermatology Service of Hospital México during the period between January 2019 and December
- •Patients aged 18 years or older, of both sexes.
- •Patients with at least one dermatological evaluation recorded during the study period.
- •Patients who, having a confirmed diagnosis, have received some modality of treatment, including skin-directed therapies (phototherapy, topical treatments, localized radiotherapy) and/or systemic treatments.
排除标准
- •Clinical records that are insufficient or incomplete, preventing adequate diagnostic classification, staging, therapeutic characterization, or evaluation of clinical evolution.
- •Patients with a presumptive diagnosis of cutaneous T-cell lymphoma without histopathological confirmation.
- •Duplicate or inconsistent records that hinder the correct identification and classification of the patient.
- •Patients attended outside the established study period.
- •Patients outside the age range.
- •Patients who do not belong to the Dermatology Service of Hospital México.
结局指标
主要结局
Characterize the epidemiology
时间窗: 2019-2025
Characterize the epidemiology of patients diagnosed with cutaneous T-cell lymphoma evaluated in the Dermatology Service of Hospital México.
Characterize the therapeutic management
时间窗: 2019-2025.
Characterize the therapeutic management of patients diagnosed with cutaneous T-cell lymphoma evaluated in the Dermatology Service of Hospital México
次要结局
- Describe the sociodemographic/epidemiological characteristics(2019-2025)
- Classify the clinical manifestations/clinical subtypes(2019-2025)
- Identify the histopathological/ immunohistochemical findings(2019-2025)
- Analyze the therapeutic management modalities.(2019-2025)
- identify the clinical stage at the time of diagnosis(2019-2025)
- Evaluation of imaging studies and laboratory.(2019-2025)
- Evaluation of clinical course and outcomes.(2019-2025)
研究者
Daniel Barquero Orias
Dermatologist
Caja Costarricense de Seguro Social