Nonalcoholic Fatty Liver Disease in Taiwanese Children
- Conditions
- Fatty Liver
- Registration Number
- NCT00274183
- Lead Sponsor
- Far Eastern Memorial Hospital
- Brief Summary
Nonalcoholic fatty liver disease (NAFLD) is an emerging and important disease in Taiwan. However, the prevalence and clinical characteristics have not been studied well. The purpose of this study is to resolve the aforementioned problem.
- Detailed Description
\[Study Subjects\] Obesity was defined as the BMI value \> 95 percentile by different age- and gender groups according to the standards of the Department of Health in Taiwan.
\[Data Collection\] The following data were obtained for each subject: age, gender, BMI, waist and hip circumference. BMI was calculated as body weight (kg)/ height (m2).
In fasting venous blood samples, we measured total serum bilirubin, alanine aminotransferase, aspartate aminotransferase, γ-glutamyltransferase, fasting glucose, triglyceride, total cholesterol,high-density lipoprotein cholesterol, insulin, glucose, and adiponectin.
\[Liver Ultrasonography\] All participants underwent an ultrasonographic study of the liver performed by one operator.
NAFLD was defined as the presence of an ultrasonographic pattern consistent with the following criteria: liver-kidney echo discrepancy, attenuated echo penetration and visibility of diaphragm, and obscure hepatic vessel structures.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 614
- diagnosis of fatty liver
- other hepatic diseases
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method non-alcoholic fatty liver disease one year confirmed by liver ultrasonography
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Far Eastern Memorial Hospital
🇨🇳Taipei, Taiwan