Can insecticide-treated curtains prevent transmission of dengue?
Not Applicable
Completed
- Conditions
- Dengue (including Dengue Haemorrhagic Fever [DHF] and Dengue Shock Syndrome [DSS])Dengue fever [classical dengue]Infections and Infestations
- Registration Number
- ISRCTN08474420
- Lead Sponsor
- iverpool School of Tropical Medicine (UK)
- Brief Summary
2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35245284/ (added 07/03/2022)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 9200
Inclusion Criteria
1. All occupied households
1.1. Persons aged 3 years or older with parental permission
1.2. Adults consenting to participate in the study living in the study area
1.3. Assent to participation for 8-17 year old persons
Exclusion Criteria
1. Persons younger than 3 years old
2. Temporary visitors to the study areas
3. Adults who do not consent to participate
4. 8-17 year old persons who do not assent or who do not have parental permission to participate in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> Effect of ITMs on dengue transmission - measured by detection of dengue specific antibodies in human blood, taken from householders within the study area, using the Plaque Reduction Neutralizing Antibody test (PRNT). PRNT is specific to dengue virus serotype, and is the gold standard against which all other dengue virus (DV) serological assays are validated.<br><br> Blood samples will be collected from the study population at baseline and at three 9-month intervals thereafter (9, 18, 24 months post intervention) in householders that were not positive for all four circulating serotypes during the immediate preceding survey.<br>
- Secondary Outcome Measures
Name Time Method