Chemotherapy inside the abdomen after surgery in patients with ovarian cancer to reduce chances of disease coming back
- Conditions
- Health Condition 1: C569- Malignant neoplasm of unspecifiedovary
- Registration Number
- CTRI/2024/08/072237
- Lead Sponsor
- Jawaharlal Institute of Postgraduate Medical Education and Research JIPMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Patient giving informed consent
Newly diagnosed FIGO stage 3 or 4a epithelial ovarian cancer
After optimal cytoreduction after interval surgery
Must have received 3 or 4 cycles of paclitaxel nd carboplatin neoadjuvant chemotherapy
ECOG performance status 0 or 1 at enrolment
Negative pregnancy test in women of child bearing potential
adequate organ function
Prior surgery for ovarian cancer other than biopsies
Serious medical illnesses
Uncontrolled infections
Pre existing neuropathy more than grade 1
Known to have borderline or low grade cancer
Prior partial therapy elsewhere
intraoperative complications rendering patient unfit for IP chemotherapy
Time from last chemotherapy to surgery less than 8 weeks
Bevacizumab as part of neoadjuvant schedule
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method