The effectiveness of a topical form of Cassia fistula L. on Constipatio
Phase 3
- Conditions
- Functional Constipation.Constipation
- Registration Number
- IRCT20170929036482N2
- Lead Sponsor
- Traditional Medicine school of Tehran University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Age between 18 to 50 years
Confirmation of functional constipation diagnosis based on Rome III criteria
Exclusion Criteria
Pregnancy, , , , , , , ,
Lactating women
History of abdominal surgery
Gastrointestinal bleeding
Psychosis
Recent surgery
Serious Heart or Liver diseases or Endocrine disorders (Diabetes, Thyroid dysfunction)
Cancer
Anemia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of defecation per week. Timepoint: Before the study, end of week 2, end of week 4. Method of measurement: A questionnaire based on Rome III criteria.;Frequency of hard stool. Timepoint: Before the study, end of week 2, end of week 4. Method of measurement: A questionnaire based on Rome III criteria.;Frequency of straining during defecation. Timepoint: Before the study, end of week 2, end of week 4. Method of measurement: A questionnaire based on Rome III criteria.;Frequency of sensation of incomplate evacuation. Timepoint: Before the study, end of week 2, end of week 4. Method of measurement: A questionnaire based on Rome III criteria.;Frequency of sensation of anorectal blockage. Timepoint: Before the study, end of week 2, end of week 4. Method of measurement: A questionnaire based on Rome III criteria.;Frequency of manual maneuvers to facilitate defecation. Timepoint: Before the study, end of week 2, end of week 4. Method of measurement: A questionnaire based on Rome III criteria.
- Secondary Outcome Measures
Name Time Method Skin complication at the site of topical use. Timepoint: Before study, end of week 2, end of week 4. Method of measurement: A questionnaire.;Any possible complications. Timepoint: Before study, end of week 2, end of week 4. Method of measurement: A questionnaire.