Comparative Evaluation of Hemocoagulase , Chitosan Dental Dressing, Cologenesis collagen plug® After Dental Extractions in Patients Undergoing Antiplatelet Therapy- A prospective clinical study

This prospective three arm clinical study evaluates the effectiveness of three local hemostatic agents applied after simple tooth extraction in adults receiving antiplatelet therapy. Participants are allocated to one of three interventions hemocoagulase solution or gel, chitosan dental dressing, or collagen plug. The primary purpose is to determine which agent achieves faster control of bleeding and supports better early wound outcomes without increasing complications. The primary outcome is time to hemostasis in minutes measured immediately after extraction. Secondary outcomes include wound healing scores on days 3, 7, and 14, postoperative pain on a visual analogue scale, secondary bleeding events, dry socket, infection, rescue measures, analgesic use, patient satisfaction, and adverse events up to 14 days. Hypothesis: at least one of the three agents will reduce time to hemostasis and improve short term postoperative outcomes compared with the others in patients on antiplatelet therapy.