Elective and Non-elective Cesarean Section and the Risk for Obesity Among Young Male Conscripts: a Population-based Cohort and Matched-sibling Analysis.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 97,291
- 试验地点
- 1
- 主要终点
- Categories of body mass index
研究概览
简要总结
Previous research has suggested that cesarean section may be associated with an increased risk of developing obesity in childhood, adolescence and adulthood. Yet, previous studies have been small or unable to differentiate between elective and non-elective cesarean section. Therefore, using a population-based cohort the purpose is to examine the associations between vaginal delivery, elective and non-elective cesarean section on the risk of developing obesity in young adulthood among Swedish young singleton males. Using the Swedish medical birth registry, the recorded mode of delivery and indication of delivery which will be matched to those males who perform military conscription, where their body mass index is recorded. The investigators hypothesize that there will be an elevated risk of obesity in those born with non-elective cesarean section, as a function of confounding, while those born with elective cesarean section will not have a higher risk of obesity than those born with vaginal delivery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Singleton birth.
- •Retrievable from medical birth registry.
排除标准
- •No available information on mode of delivery.
- •Not conscripted.
- •Extreme values at conscription.
结局指标
主要结局
Categories of body mass index
时间窗: Measured at conscription (~18 years of age)
World health organisation categories of body mass index: underweight BMI\<18.5, normal weight BMI 18.5-24.9, overweight BMI 25-29.9 and obese BMI\>30. Weight at conscription was measured using standardized scales and height was assessed using stadiometers in a standardized manner.
次要结局
- Continuous body mass index(Measured at conscription (~18 years of age))
研究者
Daniel Berglind
Principal Investigator
Karolinska Institutet
