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临床试验/NCT03918044
NCT03918044已完成不适用

Elective and Non-elective Cesarean Section and the Risk for Obesity Among Young Male Conscripts: a Population-based Cohort and Matched-sibling Analysis.

Karolinska Institutet1 个研究点 分布在 1 个国家目标入组 97,291 人开始时间: 2019年4月30日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
97,291
试验地点
1
主要终点
Categories of body mass index

研究概览

简要总结

Previous research has suggested that cesarean section may be associated with an increased risk of developing obesity in childhood, adolescence and adulthood. Yet, previous studies have been small or unable to differentiate between elective and non-elective cesarean section. Therefore, using a population-based cohort the purpose is to examine the associations between vaginal delivery, elective and non-elective cesarean section on the risk of developing obesity in young adulthood among Swedish young singleton males. Using the Swedish medical birth registry, the recorded mode of delivery and indication of delivery which will be matched to those males who perform military conscription, where their body mass index is recorded. The investigators hypothesize that there will be an elevated risk of obesity in those born with non-elective cesarean section, as a function of confounding, while those born with elective cesarean section will not have a higher risk of obesity than those born with vaginal delivery.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
Male
接受健康志愿者

入选标准

  • Singleton birth.
  • Retrievable from medical birth registry.

排除标准

  • No available information on mode of delivery.
  • Not conscripted.
  • Extreme values at conscription.

结局指标

主要结局

Categories of body mass index

时间窗: Measured at conscription (~18 years of age)

World health organisation categories of body mass index: underweight BMI\<18.5, normal weight BMI 18.5-24.9, overweight BMI 25-29.9 and obese BMI\>30. Weight at conscription was measured using standardized scales and height was assessed using stadiometers in a standardized manner.

次要结局

  • Continuous body mass index(Measured at conscription (~18 years of age))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Daniel Berglind

Principal Investigator

Karolinska Institutet

研究点 (1)

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