A pilot study of Focal Ablative Stereotactic Radiosurgery for Cancers of the Kidney or Isolated Adrenal Metastases.

Phase 2

Completed

• Conditions: Primary Renal Cell Carcinoma; Cancer - Kidney; Cancer - Other cancer types; Metastatic non-small cell carcinoma to the adrenal gland

• Registration Number: ACTRN12612000759897
• Lead Sponsor: Dr Shankar Siva

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-07-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Age > 18 years old
-All patients must have radiological diagnosis or biopsy confirmed diagnosis of either:
(a) Cohort 1: renal cell carcinoma with a single lesion within kidney, or with primary kidney tumour intact and no more than 5 documented metastases, or
(b) Cohort 2: solitary adrenal metastases with with primary disease controlled
-ECOG performance of 0-2 inclusive.
-Either medically inoperable, technically high risk for surgery or decline surgery.
-Informed consent.

Exclusion Criteria

-Cytotoxic chemotherapy within 3 weeks of commencement of treatment, or concurrently with treatment. Targeted agents (such as sunitinib) are allowable.
-Any patient who is currently pregnant or breastfeeding.
-Previous high-dose radiotherapy to upper abdomen

Study & Design

• Study Type: Interventional
• Study Design: Not specified