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临床试验/NCT05701449
NCT05701449尚未招募不适用

Prevention and Treatment of Perioperative Lung Injury in Elderly Patients

Wuhan Union Hospital, China0 个研究点目标入组 5,000 人开始时间: 2023年1月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
5,000
主要终点
Postoperative pulmonary complications

研究概览

简要总结

This study aims to verify the prediction model of postoperative pulmonary complications by collecting clinical information on elderly patients. In addition, the incidence of postoperative pulmonary complications in elderly patients before and after using the prediction model was compared.

详细描述

More than 300 million major operations are performed worldwide each year, and older patients account for about a third of elective operations. Compared with young people, the elderly are more prone to postoperative complications due to age-related degeneration of the physiological functions of various organs and tissues. Postoperative pulmonary complications, including pneumonia, atelectasis, and respiratory failure, are common. Even mild pulmonary complications can lead to the prolonged hospital stay and increased postoperative mortality.

Although there have been many studies on postoperative lung complications, there have been few studies on elderly patients. In our country, the real incidence data of elderly patients after a perioperative period of pulmonary complications, the lack of effective prevention, intervention measures, and targeted prevention and treatment technology, these reasons lead to the clinical diagnosis and treatment of elderly patients after a perioperative period of pulmonary complications are very difficult. Therefore, the research team intends to verify the established prediction model of postoperative pulmonary complications and compare the incidence of postoperative pulmonary complications in elderly patients before and after using the prediction model.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Other

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 65 years or older
  • receiving invasive ventilation during general anesthesia for surgery

排除标准

  • preoperative mechanical ventilation
  • procedures related to a previous surgical complication
  • a second operation after surgery within one week
  • organ transplantation
  • discharged within 24 hours after surgery

结局指标

主要结局

Postoperative pulmonary complications

时间窗: within one week after surgery

次要结局

  • Length of postoperative hospital stay(6 weeks after surgery)
  • Postoperative Death(6 weeks after surgery)

研究者

发起方
Wuhan Union Hospital, China
申办方类型
Other
责任方
Sponsor

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