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Clinical Trials/NCT05701449
NCT05701449
Not yet recruiting
Not Applicable

Prevention and Treatment of Perioperative Lung Injury in Elderly Patients

Wuhan Union Hospital, China0 sites5,000 target enrollmentJanuary 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Pulmonary Complications
Sponsor
Wuhan Union Hospital, China
Enrollment
5000
Primary Endpoint
Postoperative pulmonary complications
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

This study aims to verify the prediction model of postoperative pulmonary complications by collecting clinical information on elderly patients. In addition, the incidence of postoperative pulmonary complications in elderly patients before and after using the prediction model was compared.

Detailed Description

More than 300 million major operations are performed worldwide each year, and older patients account for about a third of elective operations. Compared with young people, the elderly are more prone to postoperative complications due to age-related degeneration of the physiological functions of various organs and tissues. Postoperative pulmonary complications, including pneumonia, atelectasis, and respiratory failure, are common. Even mild pulmonary complications can lead to the prolonged hospital stay and increased postoperative mortality. Although there have been many studies on postoperative lung complications, there have been few studies on elderly patients. In our country, the real incidence data of elderly patients after a perioperative period of pulmonary complications, the lack of effective prevention, intervention measures, and targeted prevention and treatment technology, these reasons lead to the clinical diagnosis and treatment of elderly patients after a perioperative period of pulmonary complications are very difficult. Therefore, the research team intends to verify the established prediction model of postoperative pulmonary complications and compare the incidence of postoperative pulmonary complications in elderly patients before and after using the prediction model.

Registry
clinicaltrials.gov
Start Date
January 2023
End Date
December 2023
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Wuhan Union Hospital, China
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age 65 years or older
  • receiving invasive ventilation during general anesthesia for surgery

Exclusion Criteria

  • preoperative mechanical ventilation
  • procedures related to a previous surgical complication
  • a second operation after surgery within one week
  • organ transplantation
  • discharged within 24 hours after surgery

Outcomes

Primary Outcomes

Postoperative pulmonary complications

Time Frame: within one week after surgery

Secondary Outcomes

  • Length of postoperative hospital stay(6 weeks after surgery)
  • Postoperative Death(6 weeks after surgery)

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