Effect of Aspirin in prevention of permanent hemodialysis catheter thrombosis

Phase 3

• Conditions: Chronic kidney disease.; Chronic kidney disease, stage 5

• Registration Number: IRCT20181128041785N1
• Lead Sponsor: Ardabil University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 March 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 114

Inclusion Criteria

ESRD Patient Requiring Permanent Hemodyalisis Catheter
Patients Candidate For Hemodyalisis Catheter Replacement

Exclusion Criteria

Blood loss Requiring Either Hospitalization Or Transfusion In The Previous 3 Months
Advanced Proliferative Diabetic Retinopathy
Life Expectancy < 12 Months Because Of Advanced Organ-Systemic Disease Or Malignancy
Uncontrolled Systolic Blood Pressure, BP > 200 mmHg Or Diastolic BP >110 mmHg On Three Different Occasions In A Period Of 2 Weeks
Platelet count < 100,000
INR > 1.3
Partial Thromboplastin Time 5 Seconds Longer Than Control
Patients Receiving Dipyridamole ,Sulfinpyrazone ,Ticlopidine , Clopidogrel ,Or Nonsteroid Anti-inflammatory Drugs
All Bleeding Episode After Aspirin Use Leeding HB Loss>1 Gr/Dl
Catheter Dysfunction From Insertion
Catheter Site Infection
Catheter Replacement More Than 3 Times
Previous Coagulopathy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Catheter Thrombosis. Timepoint: At the begining, Catheter dysfunction in first 3 month. Method of measurement: Direct vision of catheter thrombosis, venous Doppler sonography.