The effect of zinc supplementation on fatty liver

Phase 3

• Conditions: on Alcoholic Fatty Liver Disease.; Fatty (change of) liver, not elsewhere classified; K76.0

• Registration Number: IRCT20191015045113N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 December 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Attention to fatty liver confirmed by ultrasound
- Ages between 18 and 70 years
-Not consuming alcoholic beverages
- Lack of other liver diseases such as viral hepatitis, liver cirrhosis, Wilson's disease ...
- Lack of parenteral nutrition
-No diseases that affect the bile and bile ducts
- No severe weight loss 6 months ago
-Not taking medications that cause fatty liver (methotrexate, tamoxifen, valproate, etc.)
-No pregnancy and breastfeeding
- Lack of serum ALT levels more than 10 times the limit
- No chemotherapy during the past year
-Not taking any supplements containing zinc

Exclusion Criteria

People who have done chemotherapy over the past year
People with any biliary disease
People taking any supplements and drugs containing zinc
People who have had severe weight loss in the past 6 month
People taking any form of fatty liver medication

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum zinc. Timepoint: 8 weeks. Method of measurement: Blood sampling.;Insulin resistance. Timepoint: 8 weeks. Method of measurement: Blood sampling.;ALT. Timepoint: 8 Week. Method of measurement: blood sample.

Secondary Outcome Measures

Name	Time	Method
Fasting blood sugar. Timepoint: 8 week. Method of measurement: blood sample.;Serum total cholesterol. Timepoint: 8 week. Method of measurement: blood sample.;Serum triglyceride. Timepoint: 8 Week. Method of measurement: blood sample.;MDA. Timepoint: 8 week. Method of measurement: blood sample.;Total Antioxidant Capacity (TAC). Timepoint: 8 week. Method of measurement: blood sample.;Hs-CRP. Timepoint: 8 week. Method of measurement: blood sample.