Peak Systolic Global Longitudinal Strain and Low Cardiac Output Syndrome After Cardiac Surgery

Completed

• Conditions: Low Cardiac Output Syndrome After Adult Cardiac Surgery

• Registration Number: NCT02771080
• Lead Sponsor: University of Liege

Brief Summary

This is a retrospective observational study to assess the relationship between peak systolic global longitudinal strain measured on pre-cardiopulmonary bypass trans-esophageal echo images predicts post-operative low cardiac output syndrome defined as the need for an inotropic support during 24 hours or longer.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-05-11
• Study First Submitted QC: 2016-05-11
• Study First Posted: 2016-05-12
• Status Verified: 2016-06
• Study Start: 2016-06
• Primary Completion: 2016-09
• Study Completion: 2016-09
• Last Update Submitted: 2016-11-22
• Last Update Posted: 2016-11-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 275

Inclusion Criteria

• Cardiac surgery involving the use of cardiopulmonary bypass
• Availability of pre-cardiopulmonary bypass trans-oesophageal echo images allowing measurement of the peak systolic global longitudinal strain

Exclusion Criteria

• Preoperative atrial fibrillation
• Preoperative critical state
• Emergent/salvage surgery
• Heart transplant surgery
• Left ventricular assist device implantation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post-operative low cardiac output syndrome	30 days	Need for pharmacological inotropic support during 24 hours or more post-operatively

Secondary Outcome Measures

Name	Time	Method
Length of hospital stay	30 days
Need for readmission to the intensive care	30 days
duration of post-operative mechanical ventilation	30 days
Length of intensive care unit stay	30 days
30-day or in hospital mortality	30 days
post-operative acute kidney injury	30 days