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临床试验/NCT01820546
NCT01820546已完成不适用

Flow Cytometric Definition and Prognostic Effects of Multiple Myeloma Cancer Stem Cells

Ankara University1 个研究点 分布在 1 个国家目标入组 96 人开始时间: 2013年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
96
试验地点
1
主要终点
Treatment Response

研究概览

简要总结

In multiple myeloma "cancer stem" cells can be defined and quantified with flow cytometry. More, these cells can be related to treatment response.

详细描述

The investigators' hypothesis is that, multiple myeloma plasma cells derivate from principal cells that is called "cancer or progenitor stem cell". In multiple myeloma to define immunophenotyping features of these "cancer stem cells" with flow cytometry and to show their prognostic value and check for any relationship between cancer stem cell quantification and chemotherapy response are main aims of this study.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • New Diagnosed or Relapsed Multiple Myeloma
  • Routine Bone Marrow Aspiration will be done

排除标准

  • Bone Marrow Aspiration is not Needed

结局指标

主要结局

Treatment Response

时间窗: 3 months

After 3 courses chemotherapy treatment response

次要结局

  • Treatment Response(6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mehmet Ozen

MD

Ankara University

研究点 (1)

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