the Potential Immunomodulatory Effects of Spirulina on Thalassemic Children

Not Applicable

Completed

• Conditions: Beta Thalassemia Major
• Interventions: Dietary Supplement: Spirulina

• Registration Number: NCT02674607
• Lead Sponsor: Tanta University

Brief Summary

The aim of this study is to evaluate the possible immunologic effects of spirulina in children with beta thalassemia.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-10
• Study First Submitted: 2016-02-01
• Study First Submitted QC: 2016-02-03
• Study First Posted: 2016-02-04
• Status Verified: 2017-10
• Primary Completion: 2017-10
• Study Completion: 2017-10
• Last Update Submitted: 2017-10-24
• Last Update Posted: 2017-10-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• children with thalassemia major

Exclusion Criteria

• children with other chronic hemolytic anemias

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
patients	Spirulina	thirty children with beta thalassemia major will receive oral spirulina (tablets=500 mg) for 3 months with a dose of 250 mg/kg/day (maximum dose 4 gm)

Primary Outcome Measures

Name	Time	Method
cluster of differentiation (CD4/CD25) ratio	3 months
serum immunoglobulins levels	3 months
serum levels of interferon gamma	3 months
cluster of differentiation (CD33/CD11b/Lin) ratio	3 months

Trial Locations

Locations (1)

Faculty of Medicine- Tanta University; 🇪🇬 Tanta, Gharbia, Egypt