ink between heart attack and Clonal Hematopoiesis of Indeterminate Potential : A Case Control Study
Not Applicable
- Conditions
- Health Condition 1: I219- Acute myocardial infarction, unspecified
- Registration Number
- CTRI/2023/06/053398
- Lead Sponsor
- POST GRADUATE INSTITUE OF MEDICAL EDUCATION AND RESEARCH CHANDIGARH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients with Acute Coronary Syndrome (ST elevation Myocardial Infarction and Non-ST elevation Myoacardial Infarction) presenting to cardiac critical care and emergency will be recruited into the study.
Exclusion Criteria
EXCLUSION CRITERIA:
Unwilling to participate in the study
Age less than 30 years
Haematological or solid organ malignancy
Diabetes mellitus duration more than 10 years
Smokers
Prior history of Coronary Artery Disease
Peripheral artery disease
Anemia, Hemoglobin <11.9 gm/dl in females and <13.6 gm/dl in males
Platelets <1 lakh/microL
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PRIMARY OUTCOMES <br/ ><br>1.To compare the odds of having CHIP(Clonal hematopoiesis of Indeterminate Potential) mutations in patients with Acute Coronary Syndrome when compared to healthy population <br/ ><br>Timepoint: At baseline after diagnosis of Acute Coronary Syndrome
- Secondary Outcome Measures
Name Time Method SECONDARY OUTCOMES: <br/ ><br>1.Echocardiographic and angiographic co-relation in patients who are CHIP(Clonal hematopoiesis of Indeterminate Potential)carriers. <br/ ><br>2.Co-relation of pro inflammatory markers such as CRP with CHIP(Clonal hematopoiesis of Indeterminate Potential). <br/ ><br> <br/ ><br>Timepoint: At baseline after diagnosis of Acute Coronary Syndrome