Effectiveness of Mobile Chat Messaging for Preventing Relapse in Smokers Who Have Recently Quit Smoking: a Randomised Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 590
- 试验地点
- 2
- 主要终点
- Biochemically validated tobacco abstinence
研究概览
简要总结
Most smokers return to smoking (relapse) after making a quit attempt, but evidence of effective intervention to prevent relapse is scarce. Taking advantage of recent advances in mobile technologies, this study aims to evaluate the effectiveness of a mobile chat messaging-based relapse prevention intervention in promoting successful quitting in people who recently quit smoking (recent abstainers) using a randomised controlled trial design.
详细描述
Most smokers who made quit attempts and achieved short-term abstinence return to smoking (relapse) over time, even when aided by effective smoking cessation treatment. Since relapse mostly occurred in the first 4 weeks of abstinence, relapse prevention in the early phase of abstinence could potentially boost long-term abstinence. Several behavioural interventions for smoking relapse prevention have been proposed and tested in RCTs. Yet, a 2019 Cochrane review did not find traditional approaches, including self-help materials, telephone counselling and group therapy, effective in increasing long-term abstinence at 6 months or longer.
The widespread use of mobile devices has provided a highly accessible and scalable means for novel behavioural interventions for smoking cessation. A formative qualitative study in current smokers conducted by the investigators showed that mobile chat messaging is a feasible and acceptable platform for delivering smoking cessation support. A subsequent cluster randomised controlled trial on 1148 smokers found that mobile chat messaging combined with brief intervention was effective in increasing biochemically validated abstinence at 6 months. Nonetheless, whether mobile chat messaging could prevent relapse in recent abstainers has remained untested.
The investigators did a pilot trial to confirm the feasibility and acceptability of mobile chat messaging for relapse prevention in recent abstainers. This study aims to evaluate the effectiveness of mobile chat messaging relapse prevention intervention in promoting abstinence in recent abstainers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Hong Kong residents aged 18 years or above
- •Own a smartphone with WhatsApp installed
- •Enrolled in a smoking cessation program under Tung Wah Group of Hospitals Integrated Centre on Smoking Cessation
- •Smoked daily before the present quit attempt
- •Abstained from smoking for 3 to 30 days
排除标准
- •Diagnosed with a mental disease or on regular psychotropic drugs
- •Participating in other ongoing smoking cessation studies
结局指标
主要结局
Biochemically validated tobacco abstinence
时间窗: 6 months after randomisation
Verified by an exhaled carbon monoxide level of lower than 5 parts per million or a negative salivary cotinine test
次要结局
- Biochemically validated tobacco abstinence(12 months after randomisation)
- Self-reported 6-month prolonged tobacco abstinence(6 months after randomisation)
- Self-reported 7-day point prevalent tobacco abstinence(12 months after randomisation)
- Self-reported relapse rate(12 months after randomisation)
- Self-reported 12-month prolonged tobacco abstinence(12 months after randomisation)
研究者
Tzu Tsun Luk
Research Assistant Professor
The University of Hong Kong