NCT02792153撤回1 期
Estradiol and Fear Extinction for Calorie-Dense Foods in Weight Restored Adult Women With Anorexia Nervosa (AN)
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Electrodermal skin conductance activity (EDA) during a test meal
研究概览
简要总结
The purpose of this study is to determine whether estrogen may help reduce fear of high calorie-density foods in weight-restored women with Anorexia Nervosa (AN).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Estrogen
Experimental
AN participants receive a course of transdermal estradiol treatment.
干预措施: Estradiol (Drug)
结局指标
主要结局
Electrodermal skin conductance activity (EDA) during a test meal
时间窗: Baseline (day 1) and post-treatment (day 21)
Meal-related anxiety will be estimated from EDA recordings during a 90 minute test meal session pre- and post-treatment (day 1 and day 21). EDA will be reported as the rate of peaks (\>0.02 microsiemens) per second and the average skin conductance level (in microsiemens).
次要结局
- Salivary cortisol concentration during a test meal(Baseline (day 1) and post-treatment (day 21))
- Heart rate variability during a test meal(Baseline (day 1) and post-treatment (day 21))
- Subjective ratings of anxiety(Baseline (day 1) and post-treatment (day 21))
研究者
研究点 (1)
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