Skip to main content
Clinical Trials/NCT07595861
NCT07595861CompletedNot Applicable

Recovery Trajectories After Cruciate Retaining And Posterior Stabilized Total Knee Arthroplasty

Ondokuz Mayıs University1 site in 1 country40 target enrollmentStarted: April 1, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
40
Locations
1

Study Overview

Brief Summary

This prospective cohort study aimed to compare recovery trajectories following cruciate-retaining (CR) and posterior-stabilized (PS) total knee arthroplasty (TKA) using rehabilitation-centered patient-reported outcome measures (PROMs). Forty patients undergoing primary unilateral TKA were evaluated preoperatively and at 3 and 6 months postoperatively. Outcomes included pain intensity, functional status, kinesiophobia, health-related quality of life, and joint awareness assessed using validated PROMs including the Visual Analog Scale (VAS), WOMAC, Tampa Scale for Kinesiophobia (TSK), SF-36, and Forgotten Joint Score-12 (FJS-12). The study investigated whether posterior cruciate ligament management influences early postoperative recovery trajectories after TKA.

Detailed Description

Total knee arthroplasty (TKA) is an effective surgical intervention for patients with advanced knee osteoarthritis who experience persistent pain and functional limitations despite conservative treatment. Among contemporary implant designs, cruciate-retaining (CR) and posterior-stabilized (PS) prostheses are the most widely used approaches. CR implants preserve the posterior cruciate ligament (PCL) to maintain more physiological knee kinematics, whereas PS implants substitute PCL function through a post-cam mechanism. Although both designs have demonstrated successful clinical outcomes, evidence regarding their comparative influence on postoperative recovery remains inconclusive.

In recent years, postoperative evaluation after TKA has increasingly emphasized rehabilitation-centered patient-reported outcome measures (PROMs) rather than solely clinician-based assessments. Parameters such as pain, functional status, quality of life, kinesiophobia, and joint awareness provide a more comprehensive understanding of patient recovery and adaptation after surgery. However, studies directly comparing CR and PS TKA from this multidimensional rehabilitation perspective remain limited.

This single-center prospective cohort study was conducted at the Department of Orthopedics and Traumatology, Ondokuz Mayıs University Health Application and Research Center. Patients aged 50 years or older undergoing primary unilateral TKA were included. Participants were allocated to CR or PS groups according to intraoperative surgical decision-making based on posterior cruciate ligament integrity, soft-tissue balance, and routine surgical practice. Standardized perioperative management and postoperative rehabilitation protocols were applied to all participants.

Pain intensity was assessed using the Visual Analog Scale (VAS), functional status with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), kinesiophobia with the Tampa Scale for Kinesiophobia (TSK), and health-related quality of life with the Short Form-36 Health Survey (SF-36). Joint awareness was evaluated postoperatively using the Forgotten Joint Score-12 (FJS-12). Assessments were performed preoperatively and repeated at 3 and 6 months after surgery.

The primary objective of the study was to compare longitudinal recovery trajectories between CR and PS TKA designs across rehabilitation-related PROMs. The study further aimed to determine whether posterior cruciate ligament management influences pain reduction, functional recovery, psychosocial adaptation, and joint awareness during the early postoperative period.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
50 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Patients scheduled for primary unilateral total knee arthroplasty (TKA).
  • Ability to read and understand Turkish.
  • Full orientation in person, place, and time.
  • Voluntary participation with informed consent.
  • Surgery performed at the same institution under standardized perioperative and postoperative care protocols.

Exclusion Criteria

  • Revision total knee arthroplasty.
  • Presence of neuromuscular or neurological disorders affecting gait (e.g., stroke, Parkinson disease, myopathies).
  • Cognitive impairment or diagnosed psychiatric disorders that may interfere with questionnaire completion or participation.
  • Perioperative complications such as excessive bleeding, infection, prosthesis dislocation, or deep venous thrombosis.

Investigators

Sponsor
Ondokuz Mayıs University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

MİNE PEKESEN KURTÇA

Assistant Professor

Ondokuz Mayıs University

Study Sites (1)

Loading locations...

Similar Trials