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Effect of systemic melatonin in periodontal therapy

Phase 4
Conditions
Health Condition 1: M278- Other specified diseases of jaws
Registration Number
CTRI/2022/12/048262
Lead Sponsor
Other self
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.systemically healthy Subjects with periodontal disease indicated for flap surgery

2. Subjects with three/two walled intrabony defects that can be regenerated

Exclusion Criteria

1. Subjects without periodontal disease

2. Subjects with periodontal disease not requiring regenerative therapy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
evel of alkaline phosphatase and bone sialoprotein at baseline and 4 weeks after interventionTimepoint: at baseline and 4 weeks after intervention
Secondary Outcome Measures
NameTimeMethod
Clinical parameters: probing depth, clinical attachment lossTimepoint: Base line, 3 months;Levels of melatoninTimepoint: Baseline, 1 month
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