Clinical and Histological Evaluation of Demineralized Bone Allograft and Lyophilized Equine Bone Allograft for Sinus Lift: Double Blind, Parallel, Randomized Clinical Trial.

University of L'Aquila0 sites16 target enrollmentJune 2011

ConditionsMaxillary Sinus Floor Augmentation

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Maxillary Sinus Floor Augmentation
Sponsor: University of L'Aquila
Enrollment: 16
Primary Endpoint: Histomorphometric Evaluation of New Bone Formation.
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

The sinus infiltration technique for sinus floor elevation has been used successfully when a reduced vertical height is available in the posterior maxilla. However, the effect of the different graft material on the volume and on the quality of new bone formed has not been fully investigated. The aim of this study is to evaluate the clinical and histological effect of a test material, lyophilized equine bone (Bio-gen®), compared with control material, deproteinized bovine bone (Endobon®), in the sinus lift techniques with lateral approach.

Registry

clinicaltrials.gov

Start Date

June 2011

End Date

October 2015

Last Updated

6 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University of L'Aquila

Responsible Party

Principal Investigator

Enrico Marchetti

assistant professor

University of L'Aquila

Eligibility Criteria

Inclusion Criteria

•bilateral atrophy of the maxilla;
•bone ridge \<= 6mm

Exclusion Criteria

•severe systemic diseas (ASA III -IV) bisphosphonate therapy or a history of up to 3 years history of radiation therapy to neck and head area sinusitis pregnancy subjects not able to consent to participate in the study.