Demographics and Clinical Characteristics of Ocular Inflammatory Diseases in Singapore
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Distribution of demographics, diagnosis, clinical features, treatment and outcomes
研究概览
简要总结
This is a retrospective study analyzing demographics, clinical characteristics, treatment received, and outcomes of ocular inflammatory diseases that presented to the Singapore National Eye Centre (SNEC).
详细描述
This is a retrospective, cross-sectional study. In this study, the investigators aim to investigate demographics, clinical characteristics, treatment received, and outcomes of ocular inflammatory diseases, including masquerade syndromes such as ocular neoplasms (e.g., vitreoretinal and uveal lymphoma) and endophthalmitis that presented to the Singapore National Eye Centre (SNEC). Data on demographics, clinical features, diagnosis, investigations, secondary complications, treatment received, and outcomes will be analyzed using statistical software. The results of this study will lead to an improved clinical practice with better treatment selections and an optimized monitoring protocol for follow-up care for patients with ocular inflammatory diseases, including masquerade syndromes such as ocular neoplasms (e.g.,vitreoretinal and uveal lymphoma) and endophthalmitis. This will lead to better clinical outcomes and prevention of serious sight-threatening complications.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 21 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with uveitis
- •Patients diagnosed with scleritis or episcleritis
- •Patients diagnosed with ocular neoplasms e.g., vitreoretinal and uveal lymphoma
- •Patients diagnosed with endophthalmitis
- •Diagnosis confirmed by laboratory testing or histopathological examination
- •Patients diagnosed and managed at the Singapore National Eye Centre (SNEC)
排除标准
- •Patients with less than two years of clinical follow-up
- •Patients with incomplete diagnostic confirmation (i.e., lacking laboratory or histopathological evidence)
- •Patients diagnosed outside of Singapore National Eye Centre (SNEC)
- •Cases with missing key clinical or outcome data
结局指标
主要结局
Distribution of demographics, diagnosis, clinical features, treatment and outcomes
时间窗: January 1987 and January 2025
Percentage ethnic distribution, percentage of gender distribution, percentage of age distribution, percentage of etiology, percentage of clinical features, percentage of investigations, percentage of diagnosis, percentage of secondary complications, percentage of treatment received, percentage of outcomes
次要结局
- Correlation of demographics, diagnosis, clinical features, and treatment outcomes(January 1987 and January 2025)
研究者
Samanthila Waduthantri
Principal Resident Physician
Singapore National Eye Centre