MedPath

Monitoring Resynchronization in Cardiac Patients

Completed
Conditions
heart failure
heart rhythm disturbances
10007521
Registration Number
NL-OMON35090
Lead Sponsor
Medtronic Trading NL BV
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
60
Inclusion Criteria

Patients with a CRT-D indication
Patient is willing and able to use the Medtronic Carelink Network

Exclusion Criteria

- Permanent AT/AF
- CRT-D replacement patients

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Phase 1.<br /><br>Primary Endpoint<br /><br>Mean time between event onset time and clinical decision for<br /><br>each subject.<br /><br><br /><br><br /><br>Phase 2<br /><br>Secondary Endpoints<br /><br>1. mean time from clinical decision for any relevant event to<br /><br>the end of the event, adjudicated by the Event Adjudication<br /><br>Committee.<br /><br>2. QoL as measured by the MNLWHF and the EQ-5D<br /><br>questionnaires on a per subject basis.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Phase 2.<br /><br>Primary Endpoint: death from any cause, cardiovascular and<br /><br>device-related hospitalizations (at least 48 hours stay),<br /><br>calculated using a time to first event analysis.<br /><br><br /><br>Phase 2:<br /><br>Secondary Endpoints.<br /><br>1. Rate of hospitalizations on a per subject basis.<br /><br>2. Number of days spent in hospital (including hospitalizations,<br /><br>exams, in-office visits and ED admissions) on a per subject<br /><br>basis.<br /><br>3. Costs of healthcare resources (including hospitalizations,<br /><br>exams, in-office visits and ED admissions) on a per subject<br /><br>basis.<br /><br>4. QoL as measured by the MNLWHF and the EQ-5D<br /><br>questionnaires a per subject basis.<br /><br>5. Proportion of patients who receive optimal medical treatment<br /><br>for AF.</p><br>
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