Comparison between intravenous Midazolam and intravenous Fentany in flexible bronchosopy.
- Conditions
- Unspecified acute lower respiratory infection,
- Registration Number
- CTRI/2023/11/059704
- Lead Sponsor
- Department of Respiratory Medicine, KMC Manipal
- Brief Summary
To study the effects of intravenous Midazolam (0.035mg/kg) and intravenous Fentanyl (50mcg) on patient response to flexible bronchoscopy.
To assess and compare the patient response and comfort in flexible bronchoscopy done under intravenous Midazolam and intravenous Fentanyl.
To assess and compare the attenuation of pressor response in flexible bronchoscopy done under intravenous Midazolam and intravenous Fentanyl.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 72
All patients in the age group 18 to 70 years, weighing 50-85kg and undergoing flexible bronchoscopy in the Department of Respiratory Medicine.
Patients with known or suspected allergy to Midazolam and Fentanyl, patients with Renal impairment, Hepatic impairment, seizure disorder, Psychiatric illness, hemodynamic instability including cardiac failure, second or third degree heart block, heart rate less than 50/ minute, COPD patients with Forced Expiratory Volume less than 50%, Pregnancy and Lactation, Oxygen saturation less than 90%, Platelet count less than 50, 000/ cubic milli meters.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Composite score during the bronchoscopy procedure at the level of nasopharynx for 1 minute and at the time of passage through trachea for 1 minute
- Secondary Outcome Measures
Name Time Method 1. Ease of Performing bronchoscopy 2. pain and distress measured by Numerical Rating Scale
Trial Locations
- Locations (1)
KMC MANIPAL
🇮🇳Udupi, KARNATAKA, India
KMC MANIPAL🇮🇳Udupi, KARNATAKA, IndiaDr Manish R ShettyPrincipal investigator9483870029manishr213@gmail.com