Association Between Multiple Coagulation-related Factors and Lymph Node Metastasis in Patients With Gastric Cancer: A Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 516
- 试验地点
- 1
- 主要终点
- Preoperative coagulation-related factors (fibrinogen levels) of patients
研究概览
简要总结
We initially selected a total of 1128 patients with primary gastric cancer who presented at Shandong Provincial Hospital between January 2018 and October 2022, and retrospectively collected their clinical and pathological data. And retrospectively analyzed preoperative baseline characteristics, preoperative laboratory tests, and postoperative pathological results for these patients
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with primary gastric malignant tumors,
- •patients who underwent radical resection of gastric cancer,
- •patients with a postoperative pathology of adenocarcinoma or signet ring cell carcinoma according to the WTO pathological classification,
排除标准
- •patients who have distant metastases, such as liver or lung metastases, were found on preoperative ultrasound and computed tomography (CT) examinations,
- •patients who have received preoperative neoadjuvant chemotherapy,
- •patients who take anticoagulant drugs (such as aspirin) prior to surgery,
- •patients who had any previous coagulation disorder.
结局指标
主要结局
Preoperative coagulation-related factors (fibrinogen levels) of patients
时间窗: Three years
Fibrinogen levels (g/L). Measure the data of preoperative fibrinogen levels in 516 gastric cancer patients to see wether this indicator correlated with tumor stage in patients with gastric cancer.
Preoperative coagulation-related factors (MA values) of patients
时间窗: Three years
MA values(mm). Measure the data of preoperative MA values in 516 gastric cancer patients to see wether this indicator correlated with tumor stage in patients with gastric cancer.
Preoperative coagulation-related factors (platelet counts) of patients
时间窗: Three years
Platelet counts（x10\^9/L). Measure the data of preoperative platelet counts in 516 gastric cancer patients to see wether this indicator correlated with tumor stage in patients with gastric cancer.
Preoperative coagulation-related factors (D-dimer) of patients
时间窗: Three years
D-dimer (mg/L). Measure the data of preoperative D-dimer in 516 gastric cancer patients to see wether this indicator correlated with tumor stage in patients with gastric cancer.
Postoperative pathological results of tumor N stage.
时间窗: Three years.
Recording the postoperative pathological tumor N stage in 516 patients with gastric cancer.
Postoperative pathological results of tumor T stage.
时间窗: Three years
Recording the postoperative pathological tumor T stage in 516 patients with gastric cancer.
次要结局
未报告次要终点
研究者
Feng Tian
Director
Shandong Provincial Hospital