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临床试验/ISRCTN66068876
ISRCTN66068876已完成未知

The medicine, angioplasty, or surgery study: a randomized controlled clinical trial of three therapeutic strategies for multi-vessel coronary artery disease

Zerbini Foundation (Brazil)0 个研究点目标入组 611 人开始时间: 2006年7月27日最近更新:

试验速览

阶段
未知
状态
已完成
发起方
入组人数
611

研究概览

简要总结

2003 Results article in http://www.ncbi.nlm.nih.gov/pubmed/12970202 results 2004 Results article in http://www.ncbi.nlm.nih.gov/pubmed/15145093 results 2007 Results article in http://www.ncbi.nlm.nih.gov/pubmed/17339572 results 2009 Results article in http://www.ncbi.nlm.nih.gov/pubmed/19464462 results on the association of chronic kidney dysfunction in patients with multivessel chronic coronary artery disease 2009 Results article in http://www.ncbi.nlm.nih.gov/pubmed/19924244 results on the association of TCF7L2 polymorphism rs7903146 and coronary artery disease severity and mortality 2010 Results article in http://www.ncbi.nlm.nih.gov/pubmed/20733102 results 2010 Results article in http://www.ncbi.nlm.nih.gov/pubmed/20837925 results 2011 Results article in http://www.ncbi.nlm.nih.gov/pubmed/21283728 results 2012 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/22965975 cost analysis 2012 Results article in http://www.ncbi.nlm.nih.gov/pubmed/22965977 results 2013 Results article in http://www.ncbi.nlm.nih.gov/pubmed/23895807 results 2013 Results article in http://www.ncbi.nlm.nih.gov/pubmed/23828828 10-year follow-up results 2013 Results article in http://www.ncbi.nlm.nih.gov/pubmed/22944095 10-year results 2018 Results article in http://www.ncbi.nlm.nih.gov/pubmed/30410425 cost-effectiveness results 2020 Results article in https://pubmed.ncbi.nlm.nih.gov/30590726/ -year follow-up results (added 16/12/2020) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36137633/ (added 29/09/2022)

研究设计

研究类型
Interventional

入排标准

入选标准

  • 1. Stable angina
  • 2. Preserved left ventricular function
  • 3. Two or three vessel disease

排除标准

  • 1. Unstable angina or acute myocardial infarction requiring emergency revascularization
  • 2. Ventricular aneurism requiring surgical repair
  • 3. Left ventricular ejection fraction of less than 40%
  • 4. A history of Percutaneous Coronary Intervention (PCI) or Coronary Artery Bypass Graft (CABG) and single vessel disease
  • 5. A history of congenital heart disease
  • 6. Valvular heart disease or cardiomyopathy
  • 7. Inability to understand or cooperate with the protocol requirements or return for follow-up
  • 8. Left main coronary artery stenosis of 50% or more
  • 9. Suspected or known pregnancy
  • 10. Other coexisting condition that was a contraindication to CABG or PCI

研究者

发起方
Zerbini Foundation (Brazil)

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