The POSTIVE (Pre-Operative STatin InterVEntion) study

Phase 2

Completed

• Conditions: myocardial ischemia reperfusion injury; 10007593

• Registration Number: NL-OMON34896
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

open mitral and/or tricuspid valve surgery

Exclusion Criteria

• Statine use
• Acceptation for minimal invasive mitral valve surgery
• Inability to sign informed consent
• Less than 18 years old
• Ablation procedures
• Emergency operations
• Clinically diagnosed heart failure
• Clinically diagnosed atherosclerosis
• CABG procedures
• Use of corticosteroids (e.g. prednisone etc.)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>CRP, IL-6, ICAM1, vWF, cytokines, p-selectin, CK, troponins</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n/a</p><br>