Incidence and Effects of Sleep Apnea on Intracerebral Aneurysms - IESA-Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Blood pressure medication
研究概览
简要总结
Patients with intracerebral aneurysm will be screened for sleep apnea using out of center polysomnography/polygraphy. Baseline blood pressure and medication will be assessed. Patients will be followed for up to 5 years to examine the increase in aneurysm size, rupture rate and changes in medication.
详细描述
Patient presenting to the outpatient center for neurological of neurosurgical management of intracerebral aneurysm will be recruited. Sleep apnea will be assessed by questionnaire and out of center polygraph/polysomnography. Medication, comorbidities and blood pressure will be recorded. Change in aneurysm size and blood pressure medication will be evaluated annually for up to 5 years. Frequency of subarachnoid hemorrhage and increase in aneurysm size will be assessed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Intracerebral aneurysm
- •Age >= 18yrs.
- •Ability to give informed consent
排除标准
- •Stroke within 3 month of study inclusion.
结局指标
主要结局
Blood pressure medication
时间窗: Baseline
Blood pressure medication at baseline will be accessed.
Blood pressure
时间窗: Baseline
Blood pressure on baseline visit will be accessed.
次要结局
- Subarachnoid hemorrhage(5 years)
- Increase in size of aneurysm(5 years)
- Change in blood pressure medication(5 years)
研究者
Sebastian Zaremba
Dr. med. Sebastian Zaremba
University Hospital, Bonn