EUCTR2015-002019-13-HU
Active, not recruiting
Not Applicable
Reversal of deep pipecuronium neuromuscular block usingsugammadex: a randomized, double-blind, dosefindingstudy
niversity of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy0 sitesAugust 19, 2015
ConditionsThe effect of sugammadex dose on deep neuromuscular blockade willbe investigated, therefore patients suffering from various conditionsundergoing surgery in general anaesthesia with muscle relaxation willbe included in the study.Therapeutic area: Body processes [G] - Physiological processes [G07]
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- The effect of sugammadex dose on deep neuromuscular blockade willbe investigated, therefore patients suffering from various conditionsundergoing surgery in general anaesthesia with muscle relaxation willbe included in the study.
- Sponsor
- niversity of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy
- Status
- Active, not recruiting
- Last Updated
- 10 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patient aged 18\-65 undergoing general surgery under combined
- •general anaesthesia with neuromuscular
- •2\. ASA (American Society of Anesthesiology) physical status score 1\-3
- •3\. BMI (Body\-Mass Index) 18,5\-25
- •4\. duration of operation over 100 minutes
- •5\. need for intratracheal intubation
- •6\. supine position, at least one arm accessible
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
Exclusion Criteria
- •1\. diseases influencing neuromuscular function (myopathies, significant
- •renal or hepatic insufficiency)
- •2\. drugs influencing neuromuscular function (magnesium,
- •aminoglycosides)
- •3\. gravidity, lactation
- •4\. urgent surgery
- •5\. chronic obstructive pulmonary disease
- •6\. glaucoma
- •7\. difficult airway management possible
Outcomes
Primary Outcomes
Not specified
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