Effects of treadmill physical exercise in women with polycystic ovaries
Not Applicable
Recruiting
- Conditions
- E28.2Polycystic Ovary Syndrome
- Registration Number
- RBR-78qtwy
- Lead Sponsor
- Faculdade de Medicina de Ribeirão Preto
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- Not specified
Inclusion Criteria
Volunteers with PCOS between 18 to 39 years old; body mass Index between 18 and 39.9 kg/m2 (normal overweight and obesity grades I and II); Do not practice regular physical activity.
Exclusion Criteria
Presence of systemic disease that contraindicate to physical activity; presence of disabling musculo-skeletal disorders; use of drugs that interfere with the hypothalamic-pituitary-ovarian-axis and hormonal contraceptives; smoking, pregnant and volunteers who are not available to participate in all stages of the study.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Alterations in telomere content influenced by continuous aerobic training and interval aerobic training. The telome content will be analyzed by quantitative real time polymerase chain reaction (qPCR). The data are expressed in relative values of 2-CT in which it is expected a difference of 0.15 between the group with exercise and without exercise; and 0.20 in the different types of aerobic exercise.
- Secondary Outcome Measures
Name Time Method Changes in hormone concentrations and endocrine parameters, body composition, quality of life, anxiety, depression and sexual function mediated by the different types of training. Hormonal and endocrine components will be assessed by chemiluminescence and body composition by absorptiometry method Dual Energy X-Ray absortiometry (DEXA), skin folds and bioelectrical impedance. The quality of life will be assessed using the SF-36 questionnaire, for anxiety and depression will be used the hospital anxiety and depression scale questionaire, for evaluation of sexual function will be used the female sexual function index. Improvement in hormonal and endocrine parameters, reducing body fat and improves and / or recovery of sexual function, emotional status (anxiety and depression) and quality of life, which may vary with the type of training.