Longitudinal Study of the Clinical and Haematological Cause of Women With Antiphospholipid Antibodies.

Completed

• Conditions: Antiphospholipid Syndrome

• Registration Number: NCT00180817
• Lead Sponsor: Imperial College London

Brief Summary

This study is being done to see if there are any long term health related issues in women with APA and recurrent miscarriages.

Detailed Description

The association between APA and thrombosis is well documented. Both LA and ACA are often detected in individuals with SLE but there is no prospective data on the risk of thrombosis in women who present with recurrent miscarriages in association with APA. This study should significantly advance medical knowledge of the natural history of primary antiphospholipid syndrome (PAPS) which is essential to enable optimal management of relatively young women who may be at risk of complications, some of which are potentially life threatening.

Study Timeline

• Study Start: 1998-09
• Primary Completion: 2005-08-31
• Study Completion: 2005-08-31
• Study First Submitted: 2005-09-13
• Study First Submitted QC: 2005-09-13
• Study First Posted: 2005-09-16
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-04
• Last Update Posted: 2022-08-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 250

Inclusion Criteria

Antiphospholipid syndrome History of recurrent miscarriages

Exclusion Criteria

Previous thromboembolic disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

St. Mary's Hospital; 🇬🇧 London, United Kingdom