NCT00002284已完成不适用
A Pilot Study To Evaluate Azidothymidine (AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Infection in Patients Receiving a Bone Marrow Transplant
Glaxo Wellcome2 个研究点 分布在 1 个国家开始时间: 2001年8月31日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 试验地点
- 2
研究概览
简要总结
To determine whether zidovudine (AZT) in conjunction with bone marrow transplantation prevents the reinfection of donor hematopoietic/lymphoid cells in patients with positive HTLV III antibody and large cell/diffuse histiocytic lymphoma. Patients who are candidates will be evaluated for HTLV III activity and drug levels.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 12 Years 至 50 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Exclusion Criteria
- •Co-existing Condition:
- •Patients with current life-threatening infection at time of transplant that would preclude a transplant are excluded.
- •Concurrent Medication:
- •Other anti-retroviral agents.
- •Patients with current life-threatening infection at time of transplant that would preclude a transplant are excluded.
- •Patients must be:
- •HTLV III antibody positive by ELISA or Western blot or HTLV III viremia.
- •At high mortal risk with a diagnosis of AIDS or AIDS Related Complex (ARC).
- •Also patient must fall into one of the following categories:
- •Have an HIV seronegative identical twin to serve as a bone marrow donor.
- •Have documentation of large cell/diffuse histiocytic lymphoma/DPDL.
- •Be a good risk candidate for bone marrow transplant.
排除标准
- 未提供
研究者
研究点 (2)
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