Marfan Syndrome and Quality of Life of Pediatric Patients
- Conditions
- Rare DiseasesPediatric Disorder
- Registration Number
- NCT05748314
- Lead Sponsor
- IRCCS Policlinico S. Donato
- Brief Summary
The goal of this observational study is to learn about the impact of Marfan syndrome (MFS) in paediatric affected subjects. the main questions it aims to answer are:
* The assessment of quality of life in MFS Italian patients;
* The impact of phenotypic manifestations on self-image and self-management skills;
* Stratify patients according to the need of psychological support. Participants will take part in the study by completing four self-report questionnaires.
- Detailed Description
In literature, adolescents with MFS experience difficulty in connecting with peers, and are convinced that they would have been more physically attractive without the disease. Additionally, due to physical activity restrictions and orthopedic limitations, these patients reported having difficulty adjusting and participating in educational events.
Data from present study will be able to support clinicians in identifying patients who need psychological support (through parental counseling interviews) aimed at increasing compliance with treatments and adaptation to the disease.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 80
- Signed informed consent;
- MFS diagnosis according to Revised Ghent criteria (2010);
- Known cognitive deficits
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Psychological counseling 12 months Questionnaire to assess psychological support is Morisky Medication Adherence Scale
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
IRCCS Policlinico San Donato
🇮🇹San Donato Milanese, Lombardia, Italy