Amoxicillin study for early syphilis

Phase 4

Recruiting

• Conditions: Syphilis; Syphilis, Sexually transmitted infections, treponema pallidum; D013587

• Registration Number: JPRN-jRCT1031210615
• Lead Sponsor: Ando Naokatsu

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-02-18
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 208

Inclusion Criteria

1. Patients aged 20 years or older.
2. Patients provided an informed consent in writing.
3. Patients diagnosed with early syphilis based on the following criteria (i) positive RPR conversion or (ii) four-fold increase in RPR titer compared to previous RPR titer
4. Patients has a positive non-treponemal assay result.

Exclusion Criteria

1. Individuals with pregnancy
2. Individuals with a history of known hypersensitivity to BPG, amoxicillin or probenecid.
3. Individuals with neurosyphilis including ocular syphilis and otosyphilis.
4. Individuals with late syphilis.
5. Patients required antibiotics that effective for syphilis within the preceding three weeks
6. Person who are judged by their physicians in charge to be ineligible for any reason

Study & Design

• Study Type: Interventional
• Study Design: Not specified