NCT05828836已完成2 期
the Impact of Allopurinol of HRQOL in Cirrhotic Patients
适应症
干预措施
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Chronic liver disease questionnaire
研究概览
简要总结
The study aims to evaluate the impact of allopurinol on patients' related quality of life.
详细描述
Cirrhosis is the late stage of liver damage and possess two phases:. The shift from compensated to decompensated cirrhosis is characterized by the onset of complications) which are associated with substantial morbidity and negative Impact on quality of life (QOL)Cirrhosis and its complications have a substantial economic, social, and personal impact on affected patients, as well as their families and caregivers
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •cirrhosis adult both sex
排除标准
- •renal insufficiency
研究组 & 干预措施
placebo
Placebo Comparator
干预措施: Placebo (Drug)
allopurinol
Active Comparator
干预措施: Allopurinol Tablet (Drug)
结局指标
主要结局
Chronic liver disease questionnaire
时间窗: 6 months
effect on Chronic liver disease questionnaire score
次要结局
未报告次要终点
研究者
Khadija Ahmed Mhrose Glal
assistant lecturer
Tanta University
研究点 (1)
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