Multi-centre EuRopean study of MAjor Infectious Disease Syndromes (MERMAIDS) – Observational Study of Arboviral Compatible Febrile Illness in Hospitalised Patients

niversity of Oxford0 个研究点目标入组 1,500 人开始时间: 2016年1月21日最近更新: 2019年1月14日

适应症

试验速览

暂无简介。

•1. Adults (= 18 years old) admitted to hospital from 1st May – 31st October inclusive with recent onset (<21 days) of symptoms of suspected Encephalitis or Meningitis .
•2. Rapid onset of temp.= 38°C of unknown etiology (<21 days) AND at least ONE of the signs or symptoms below:
•2.1. A neurological symptom (such as: neck stiffness, photophobia, partial paralysis, polyradiculitis, periorbital pain, confusion, altered mental state)
•2.2. Severe headache
•2.3. Myalgia
•2.4. Backache
•2.5. Arthralgia
•2.6. Maculopapular rash
•2.7. Haemorrhagic symptom
•2.8. Thrombocytopenia (<150 000 cells per microliter of blood)

•1. Patients with non-infectious central nervous system (CNS) disorders due to hypoxic, vascular, toxic or metabolic causes
•2. Patients where the symptoms are due to another confirmed cause, such as bacterial infection, malaria, malignancy, immune disorders, trauma
•3. Patients with a focal source of infection identified, such as pneumonia, viral respiratory tract infection, acute infectious diarrhea, urinary tract infection (positive urine cultures), or skin or soft-tissue infection
•4. Patients where the symptoms are caused by recurrence of a pre-existing condition

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