Vitamins C and Vitamin E and Hypertrophy Adaptations to Resistance Traini
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 30
- Locations
- 2
- Primary Endpoint
- Manual dinamometry
Study Overview
Brief Summary
This investigations aims to investigate whether supplementation with antioxidant vitamins (vitamin C and vitamin E) can influence, enhancing or blocking, the hypertrophic adaptations caused by strength training in sedentary subjects.
Detailed Description
A randomized, double-blind, placebo-control controlled trial will be conducted. In a previous session volunteers will be interviewed to determine if they meet the inclusion criteria. Will be done two weeks of flushing out other types of supplementation and strenuous physical exercise, along with familiarization with the strength training program and performance tests to be carried out during the rehearsal. Subsequently, it will be a week without exercising to start with the experimental designs. From the start of the trial, participants should avoid physical exercise. strenuous outside the training protocol and if usual, they will only be able to perform one resistance training session per week. Participants should avoid ingesting of foods that contain high amounts of antioxidant compounds: more than two juices of fruits, more than four cups of coffee or tea. Juices with high antioxidant content should be avoided. Alcoholic beverages should also be avoided.
- Group 1 (G1): Antioxidant vitamins (VitC (1000 mg) + VitE (235 mg)) + exercise
- Group 2 (G2): Placebo + exercise A supplementation period of 12 weeks will be carried out. In each period, supplementation with antioxidant vitamins: VitC (1000 mg) + VitE (235 mg) or with placebo.
All participants will ingest the supplementation between 1-3 hours before training, the days of rest in the mornings.
All participants will perform a 12-week strength training protocol. The training session performed in the sharp design will be the first training session in chronic design. Being the baseline (E0) and post-exercise (E1) assessment performed in G1, G2 and G3 also the first evaluation corresponding to the chronic design.
In the middle of the supplementation period (week 6) and at the end, two new evaluations (week 12). Baseline evaluations will be performed prior to an exercise session of week 6 (E2) and at the last exercise session (E3) of the following parameters: performance physique, body composition, micronutrient analysis, muscle ultrasound. I also know conduct post-exercise physical performance assessments Figure 2.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Basic Science
- Masking
- Double (Participant, Investigator)
Masking Description
The provider will produce the supplementation and the placebo with the same aspect, marked with numbers
Eligibility Criteria
- Ages
- 18 Years to 30 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Experience in strength training of at least one year
Exclusion Criteria
- •Antioxidant supplementation
- •Injuries or diseases
Outcomes
Primary Outcomes
Manual dinamometry
Time Frame: Week 5
Handgrip
DOMS
Time Frame: Week 10
Delayed onset muscle soreness evaluated with visual analoguic scale (0 no pain- 10 maximal pain)
RPE
Time Frame: Week 10
10-point scale (no exertion 0- maximal effort 10)
Anthropometry
Time Frame: Week 10
Evaluation of muscle mass by a ISAK 1 level anthropometrist
Leg dinamometry
Time Frame: Week 10
Dinamometer
Parameters determined by ENCODER
Time Frame: Week 10
Bench press and squats
DEXA
Time Frame: Week 10
Evaluation of muscle mass with dual energy X-ray absorptiometry
Bioimpedance
Time Frame: Week10
Evaluation of muscle mass with an Inbody
1 RM
Time Frame: Week 10
Bench press and squats
Secondary Outcomes
No secondary outcomes reported
Investigators
María Martínez Ferrán
predoctoral researcher
Universidad Europea de Madrid
