Altered MAstication Contribute to TMJ PAin

Completed

• Conditions: Temporomandibular Joint Disorders; Mastication Disorder

• Registration Number: NCT03139994
• Lead Sponsor: University of Santiago de Compostela

Brief Summary

The cause of temporomandibular joint disorders remains unknown. It is considered multifactorial and includes physical (peripheral) and psychosocial (central) factors. It has been showed an association: a steeper condylar path, flatter lateral anterior guidance, and habitual chewing on the symptomatic side. This finding argues the possibility of causation of some of these characteristics. This double blind longitudinal study aims to assess if the presence of one habitual chewing side could contribute to temporomandibular joint disorders over time.

Method. Young adults with no signs or symptoms of TMD will be assessed. Participants with one chewing side (observed and interview); with steeper condylar path and lower lateral guidance angles will be considered consistent one side chewers, and this side will be considered more susceptible to suffer TMD. Mouth opening, hemispheric dominance and hemimandibular retrognathia will be considered as secondary pre-specified outcomes. Four years later, both TMJs of each participant presenting signs and/or symptoms will be evaluated according to DC/TMD.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-05-10
• Study First Submitted QC: 2017-05-01
• Study Start: 2017-05-02
• Study First Posted: 2017-05-04
• Primary Completion: 2018-10-15
• Study Completion: 2018-10-30
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-30
• Last Update Posted: 2021-10-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• healthies
• full dentates
• normal occlusion
• One habitual chewing side

Exclusion Criteria

• Severe malocclusion, dental decay, severe periodontal disease.

Pains from other origins or Orthodontics are not criteria for exclusion

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence or not of symptoms of temporomandibular joint disorders according to DC/TMD	At 3 years follow-up	Pain-intensity (0-10 VAS scale, Von Korf)
Change of maximal unassited jaw opening	Baseline and 3 years follow-up	Maximum unassisted jaw opening or interincisal distance (from edge to edge) measured by a Boley gauge. Up 38 in females and up 40 mm in males are considered limited.

Secondary Outcome Measures

Name	Time	Method
Change of condylar paths angles inclination	Baseline and 3-4-years follow-up (end of the study)	Alteration of parasagittal plane Axiography of condyle motion in respect Frankfort horizontal plane
Alteration of lateral dental guidance angles	Baseline and 4-years follow-up (end of the study)	Angle between Frankfort plane and lateral dental anterior guidance
Change of maximal comfortable jaw opening	Baseline and 4-years follow-up (end of the study)	Maximum jaw opening or interincisal distance (from edge to edge) measured by a Boley gauge. Up 38 in females and up 40 mm in males are considered limited.
Change of the habitual chewing side	Baseline and 3-4-years follow-up (end of the study)	Determining the habitual chewing side by direct observation using chewing gum, First cicle, and subsequent cicles (7 or over of 10 cicles), interview (used one habitual chewing side?: 1, no, alternate; 2, yes, right; 3, yes, left; 4, I don't know) and kinesiography.
Change of lateral deviation during maximal unassisted jaw opening	Baseline, 3 years follow-up	Kiesiography K7

Trial Locations

Locations (1)

University of Santiago de Compostela; 🇪🇸 Santiago de Compostela, A Coruña, Spain