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临床试验/CTRI/2026/02/104396
CTRI/2026/02/104396尚未招募不适用

To study the predictive value of neuromuscular monitor-based quantitative sensory testing for postoperative pain and opioid requirement

Dayanand Medical College and Hospital1 个研究点 分布在 1 个国家目标入组 53 人开始时间: 2026年3月3日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
53
试验地点
1

研究概览

简要总结

Effective post-operarative pain management remains a significant challenge in perioperative care of the patient. Treatment of post-operarative pain is an increasingly monitored measure for the quality of care offered to patients. Individual variability leads to varied pain experiences and affects responses to pain management among patients. Also, due to individual variability in pain sensitivity, standardized treatment protocols may not work equally well for all the patients. Although advances in analgesic techniques & multimodal pain management have improved postoperative pain control, there is still a considerable subset of patients who experience disproportionately severe pain leading to increased opioid requirement, prolonged hospital stay, delayed recovery and a higher risk of chronic post surgical pain. Anticipating such patients, who are likely to experience severe post -operative pain, could help clinicians tailor pain management strategies to improve outcomes.

Several traditional Quantitative Sensory Testing(QST) methods which includes pressure algometry, thermal testing and electrical stimulation, have shown efficacy in predicting post-operarative pain responses by assessing patients’ reaction to various sensory stimuli.

If a reliable correlation is established between preoperative stimulation response and postoperative pain intensity/opioid consumption, this method could offer a pragmatic and scalable solution for perioperative pain assessment, ultimately allowing clinicians to stratify patients based on their pain sensitivity and plan perioperative analgesia accordingly, enhancing both pain control and overall recovery.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Patients undergoing laparoscopic cholecystectomy under general anaesthesia Adults of either gender,ASA 1 and 2.

排除标准

  • Pre-existing Chronic pain or Opioid abuse/previous surgical history Neurological disorders Psychiatric illness affecting pain reporting Patients on medications affecting pain perception (e.g., antidepressants, antiepileptics).
  • Any medical condition that prevented the use of paracetamol or fentanyl in the post-operarative period Patient refusal for the study.

研究者

发起方
Dayanand Medical College and Hospital
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Shikha Gupta

Dayanand Medical College and Hospital

研究点 (1)

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