ACTRN12622000528752已完成未知
An examination into the effects of a curcumin extract (Curcugen) on energy, mood, and cognitive performance in adults experiencing stress and exhaustion: a randomised, double-blind, placebo-controlled trial
Clinical Research Australia0 个研究点目标入组 81 人开始时间: 2022年4月4日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 81
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 40 Years 至 75 Years（—）
- 性别
- All
入选标准
- •1)Healthy individuals (male and female) aged between 40 to 75 years
- •2)Residing in independent living accommodation
- •3)Experiencing exhaustion disorder as defined by the criteria set by the Swedish National Board of Health and Welfare (a score greater than or equal to 19 on the Karolinska Exhaustion Disorder Scale)
- •4)Non-smoker
- •5)BMI between 18 and 35 kg/m2
- •6)No plan to commence new treatments over the study period
- •7)Understand, willing and able to comply with all study procedures
- •8)Willing to provide a personally signed and dated informed consent form detailing all pertinent aspects of the trial.
排除标准
- •1)Diagnosis of dementia based on the revised National Institute on Aging-Alzheimer’s Association (NIA/AA) criteria
- •2)A score below the 5th percentile for age, education, and gender on the Telephone Interview for Cognitive Status (TICS-M)
- •3)Suffering from recently diagnosed or unmanaged medical conditions including but not limited to: diabetes, hyper/hypotension, cardiovascular disease, gallbladder disease, autoimmune disease, endocrine disease, or cancer/ malignancy
- •4)Diagnosis of a psychiatric disease (other than mild-to-moderate depression or anxiety) and/or neurological condition/ disease (e.g., Parkinson’s, Alzheimer’s disease)
- •5)History of paralysis, stroke or seizures or head injury (with loss of consciousness).
- •6)Regular medication intake including but not limited to anticholinergics, anti-epileptics, acetylcholinesterase inhibitors, antihistamines, benzodiazepines, opioids, or corticosteroids.
- •7)Change in medication in the last 3 months or expectation to change during the study duration
- •8)Currently taking curcumin supplements
- •9)In the last 6 months, commenced or changed dose of nutritional and/or herbal supplements that may impact on treatment outcome
- •10)Current or 12-month history of illicit drug abuse
- •11)Alcohol intake greater than 14 standard drinks per week
- •12)Pregnant women, women who are breastfeeding or women who intended to fall pregnant.
- •13)Any significant surgeries over the last year
- •14)Planned major lifestyle change in the next 3 months
研究者
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