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临床试验/NCT04516928
NCT04516928已完成不适用

Study of SARS-CoV2 Virus (COVID-19) Seroprevalence Among Lyon-Bron Military Health Schools Personnel

Direction Centrale du Service de Santé des Armées1 个研究点 分布在 1 个国家目标入组 392 人开始时间: 2020年9月21日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
392
试验地点
1
主要终点
Proportion of anti-SARS-CoV2 seropositive participants

研究概览

简要总结

Emerging in China in December 2019, Covid-19, whose pathogen is SARS-Cov-2, was declared a global pandemic in March 2020. The clinical presentation is highly variable, ranging from asymptomatic forms to acute respiratory distress and even death. Transmission is by droplet route, with an R0 of approximately 3.

Rapidly, population protection measures were put in place by governments, including the confinement of all persons whose functions were not considered essential and the closure of educational institutions.

Health care institutions are places at risk of Covid-19 transmission and hospital staff are particularly exposed, either through direct contact with patients, contact with exposed persons or through the environment. In order to protect personnel, hygiene measures were immediately recalled and reinforced.

During the period of containment, the majority of students from the Lyon-Bron Military Medical Schools were sent as reinforcement in Army Training Hospitals and in the Military Reanimation Unit (Mulhouse). Some students developed symptomatic forms of SARS-Cov-2 infection, documented by positive PCR, during Operation Resilience or on their return from the mission.

The Lyon-Bron Military Medical Schools staff, exposed both to the initial phase of the epidemic and to national protection measures, represent an extremely interesting population for understanding the epidemiological dynamics of the virus.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • at least 18 years of age
  • personnel of the Military Health Schools of Lyon-Bron
  • working at the Military Health Schools of Lyon-Bron during the COVID-19 crisis

排除标准

  • contraindication to blood sampling

结局指标

主要结局

Proportion of anti-SARS-CoV2 seropositive participants

时间窗: Day 0

The proportion of anti-SARS-CoV2 seropositive participants will be determined. ELISA serology test will be used to detect anti-SARS-CoV2 antibodies (IgG and IgM) at Day 0.

次要结局

  • Proportion of asymptomatic participants (among anti-SARS-CoV2 seropositive participants)(Day 0)
  • Correlation coefficient between social risk factors and a positive serology(Day 0)
  • Correlation coefficient between medical risk factors and a positive serology(Day 0)
  • Correlation coefficient between epidemiological risk factors and a positive serology(Day 0)

研究者

发起方
Direction Centrale du Service de Santé des Armées
申办方类型
Other
责任方
Sponsor

研究点 (1)

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