Short Term Outcomes of Laparoscopic Intersphincteric Resection for ultra Low Rectal Cancer (ISR)
Not Applicable
Recruiting
- Conditions
- Rectal cancer
- Registration Number
- PACTR201912667453983
- Lead Sponsor
- Alexandria main university hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 106
Inclusion Criteria
Patients with low rectal carcinoma (The lowest margin of tumor located 3 cm from anal verge ; ¿ 2 cm from dentate lines; 1 cm from anorectal rings.
Local spread restricted to the rectal wall or the internal anal sphincter.
Adequate preoperative sphincter function and continence.
Absence of distant metastasis.
Exclusion Criteria
Contraindications to major surgery and American Society of Anesthesiologists (ASA) Physical Status scoring 4.
Metastatic rectal cancer.
Those in Dukes stage D (T4 lesion).
Undifferentiated tumours.
Local infiltration of external anal sphincter or levator ani muscles.
Tumor located more than 2 cm above the dentate line.
Presence of fecal incontinence.
Patients unwilling to take part in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hospital stay
- Secondary Outcome Measures
Name Time Method Duration of the intervention ;Amount of blood loss and rate of blood transfusion ;The onset of intestinal motility.;Pain score ;Postoperative complications ;30 days follow up for readmission in the postoperative period ;Clinical functional outcome of intersphincteric resection;Local recurrence within 2 years ;Distant metastasis within 2 years;conversion rate for laparoscopic ISR