Exploring Pressures, Tissue Perfusion and Body Positioning: A Pilot Evaluation among critically Ill Patients (EXTREME Pressure Study)

Completed

• Conditions: critically ill patients; peak interface pressure; tissue reperfusion; Skin - Normal skin development and function; Cardiovascular - Normal development and function of the cardiovascular system

• Registration Number: ACTRN12615001341516
• Lead Sponsor: Professor Fiona Coyer

Brief Summary

The study recruited 23 ICU patients and nine healthy adult volunteers. The study found that when considering age, the sickest group of ICU patients had the highest peek pressure point readings and the healthy adults had the lowest peek pressure point readings (p=0.093). Older adults were also found to have higher peek ressure point readings when compared to younger adults. The participants body temperature was found to be related to the speed of tissue reperfusion (p=0.091). This pilot study has identifed that there is a difference in peek pressure point outcomes for levels of sickness of ICU patients and healthy volunteers, which is a first for this patient population.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-09-14
• Study Start: 2015-12-09
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

Healthy adults:
Over 18 years of age.

Critically ill patients:
Over 18 years, mechanically ventilated, SOFA score, BMI category and for the patient to remain ventilated for greater than 48 hours post recruitment to collect data.

The SOFA and BMI categories are key inclusion criteria for this study as the participants are screened to fit into the split plot study design. Participants are split into 3 health status groups: 9 healthy adults, 9 low acuity critically ill patients, 9 high acuity critically ill patients. Each health status has 3 participants in each BMI group (under 25, 25-29.9 and 30 or greater). If the BMI or SOFA group was completed, we excluded potential participants that met the criteria and only looked for participants to complete to other BMI/SOFA groups.

Exclusion Criteria

Healthy Adults:
Under 18 years of age

Critically ill patients:
Burns patients with greater than 40% total body surface area burns, burns patients with injury to the sacrum and hip region, unable to be turned in one or more of the body positions, on non-invasive ventilation (NIV), haemodynamically unstable (this will be based on the clinical nurse consultant and bedside registered nurse clinical judgement).

Study & Design

• Study Type: Interventional
• Study Design: Not specified