Early Body Temperature Targets and Relationship With Prognosis in Patients With Heat Stroke

Recruiting

• Conditions: Heat Stroke
• Interventions: Other: observation

• Registration Number: NCT05921682
• Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Brief Summary

The goal of this observational study is to explore the optimal target body temperature in first 24 hours and the relationship between body temperature and adverse outcomes of heat stroke.

The main questions it aims to answer are:

* the optimal target body temperature at 0.5 h, 2 h, and the lowest body temperature of heat stroke.

* the best body temperature at the cutting point of stop cooling.

* The relationship between the volume and speed of ice saline infusion and the cooling effect.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-05
• Study First Submitted: 2023-05-23
• Study Start: 2023-05-28
• Study First Submitted QC: 2023-06-18
• Last Update Submitted: 2023-06-18
• Study First Posted: 2023-06-27
• Last Update Posted: 2023-06-27
• Primary Completion: 2025-10
• Study Completion: 2026-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• ≥ 18 years; ② diagnosed as heat stroke; ③ Informed consent from patients or family members.

Exclusion Criteria

• need immediate cardiopulmonary resuscitation; ② transferred from another hospital; ③ with severe underlying organ insufficiency; ④ pregnant women.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with heat stroke	observation	Patients with heat stroke presenting to the emergency department at the study site

Primary Outcome Measures

Name	Time	Method
mortality	up to 90 days	Number of participants who dead during hospitalization
organ damage	up to 90 days	Number of participants with organ damage, including but not limited to brain, lung, heart, kidney, liver and coagulation

Secondary Outcome Measures

Name	Time	Method
continuous renal replacement therapy	up to 90 days	Number of participants who need CRRT
length of ICU stay	up to 90 days	The length patient stay in ICU
length of hospital stay	up to 90 days	The length patient stay in hospital

Trial Locations

Locations (6)

The Second Affiliated Hospital of Zhejiang University School of Medicine; 🇨🇳 Hangzhou, China

Jinhua Municipal Central Hospital; 🇨🇳 Jinhua, China

Yiwu Central Hospital; 🇨🇳 Yiwu, Zhejiang, China

Dongyang People's Hospital; 🇨🇳 Dongyang, China

Jinhua People's Hospital; 🇨🇳 Jinhua, China

Lanxi People's Hospital; 🇨🇳 Lanxi, China