Molecular Epidemiology of Benzene-exposed Workers.
- Conditions
- Hematologic Diseases
- Interventions
- Other: Shanghai workers
- Registration Number
- NCT00364520
- Lead Sponsor
- University of Colorado, Denver
- Brief Summary
The purpose of this study is to investigate the health effects of benzene exposure in workers in Shanghai, China.
- Detailed Description
The purpose of this study is to investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers and to characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2000
Worked for at least one year in a monitored environment Have at least one physical examination recorded
History of cancer, radiation exposure, chemotherapy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Shanghai Workers Shanghai workers Shanghai Workers
- Primary Outcome Measures
Name Time Method Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers. August 2003 - December 2009 Investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers
- Secondary Outcome Measures
Name Time Method Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity. August 2003 - December 2009 Characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.
Trial Locations
- Locations (1)
Joint Sino-US Clinical and Molecular Laboratory (JCML)
🇨🇳Shanghai, China